Reactivation of chlamydial genital tract infection in mice
نویسندگان
چکیده
منابع مشابه
Reactivation of chlamydial genital tract infection in mice.
A model was developed to study chlamydial quiescence in C3H/HeN (C3H) and C57BL/6N (C57) mice following genital tract infection by Chlamydia trachomatis MoPn. Reactivation of chlamydial shedding following immunosuppression indicated that viable MoPn remained in the genital tract for up to 4 or 5 weeks after the apparent clearance of a primary infection. Either cyclophosphamide or cortisone acet...
متن کاملCorr et al. Steroids in Chlamydial Genital Tract Infection
1 This work was supported by the NIH-NIAID via grants R01 A105624 and U19 A1084024 to T.D. and by a grant from the Magee Women’s Research Institute Clinical Trainee Research Award to T.E.C. 2 Author is now located at the Department of Pediatrics, Penn State Hershey School of Medicine, 500 University Drive, Hershey, Pennsylvania 17033. CVI Accepts, published online ahead of print on 2 April 2014...
متن کاملEarly local cytokine profiles in strains of mice with different outcomes from chlamydial genital tract infection.
In this study, we expand on the examination of genetically determined differences in host responses that correlate with clearance of Chlamydia trachomatis from the genital tract. We infected C57BL/6, BALB/c, and C3H/HeN mice with the mouse pneumonitis agent of C. trachomatis (MoPn). C57BL/6 mice had the shortest course of infection (22 days) and the lowest incidence of severe hydrosalpinx. BALB...
متن کاملChlamydial lower genital tract infection and spontaneous abortion.
OBJECTIVE Few previous studies have examined the role that acute Chlamydia trachomatis lower genital tract infection plays in the development of spontaneous abortion. This study evaluated cervical C. trachomatis infections among 52 women experiencing spontaneous abortion and 59 controls. METHODS Pregnant women at less than 22 weeks of gestation who sought medical care in an emergency departme...
متن کاملChlamydial variants differ in ability to ascend the genital tract in the guinea pig model of chlamydial genital infection.
An important question in the study of chlamydial genital tract disease is why some women develop severe upper tract disease while others have mild or even "silent" infections with or without pathology. Animal studies suggest that the pathological outcome of an infection is dependent upon both the composition of the infecting chlamydial population and the genotype of the host, along with host ph...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 1997
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.65.6.2067-2073.1997